X linked lymphoproliferative disease in a United Kingdom family
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چکیده
منابع مشابه
X linked lymphoproliferative disease in a United Kingdom family.
X linked lymphoproliferative disease (XLP; Duncan's disease) is a rare disorder affecting boys and characterised by a defective immune response to Epstein-Barr virus caused by a mutation in a gene located at chromosome Xq25. Three siblings with XLP in a single UK family are reported and the variation in phenotypic expression of the disease in these siblings described. One of the siblings with l...
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X-linked lymphoproliferative disease, also known as Duncan's syndrome, is a rare genetic disorder that causes exaggerated immune responses to Epstein-Barr virus (EBV) infection and often leads to death. Patient presentation varies but can include signs and symptoms typical of EBV, pancytopenia, and fulminant hepatitis.
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1998
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.79.1.52